TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 0.245nMAssay Description:Displacement of [3H]epibatidine from rat alpha4beta2 nAChRMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 0.309nMAssay Description:Displacement of [3H]epibatidine from rat alpha4beta2 nAChRMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 0.380nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 0.450nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 0.640nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 0.680nMAssay Description:In vitro binding affinity for Nicotinic acetylcholine receptor alpha4-beta2 (alpha4 beta-2 subtype of nAChRs) in rat cerebral cortical membrane using...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 0.870nMAssay Description:In vitro binding affinity for Nicotinic acetylcholine receptor alpha4-beta2 (alpha4 beta-2 subtype of nAChRs) in rat cerebral cortical membrane using...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 0.910nMAssay Description:Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:In vitro binding affinity for Nicotinic acetylcholine receptor alpha4-beta2 (alpha4 beta-2 subtype of nAChRs) in rat cerebral cortical membrane using...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 3.80nMAssay Description:Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:In vitro binding affinity for Nicotinic acetylcholine receptor alpha4-beta2 (alpha4 beta-2 subtype of nAChRs) in rat cerebral cortical membrane using...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 5.80nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 6.5nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 7.20nMAssay Description:Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 8.40nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 8.80nMAssay Description:Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibitory activity of the compound against nAChR mediated nicotine-evoked [3H]-DA overflow using rat striatal slicesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rat alpha4beta2 nAChR expressed in HEK cells assessed as inhibition of epibatidine-induced membrane potential preincubated for...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rat alpha4beta2 nAChR expressed in HEK cells assessed as inhibition of epibatidine-induced membrane potential preincubated for...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR was determined; experiment 1More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR was determined; experiment 2More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Evaluated for binding affinity towards nicotinic acetylcholine receptor alpha4-beta2More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibitory activity of the compound against nAChR mediated nicotine-evoked [3H]-DA overflow using rat striatal slicesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibitory activity of the compound against nAChR mediated nicotine-evoked [3H]-DA overflow using rat striatal slicesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibitory activity of the compound against nAChR mediated nicotine-evoked [3H]-DA overflow using rat striatal slicesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Instituto De Investigaciones Biol£Gicas Clemente Estable
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of [3H]-nicotine binding to Nicotinic acetylcholine receptor alpha4-beta2 in rat brainMore data for this Ligand-Target Pair